Pronto disponible para inscripción
This study will open for enrollment soon. Please contact the study team for more information and check back frequently.

BeOne-BGB-11417-304 - Clinical Trial

¿Cuál es el Propósito de este estudio?

You will be randomly assigned to one of two study arms:

• Arm A: Sonrotoclax + Zanubrutinib

• Arm B: Venetoclax + Acalabrutinib

The study includes Screening (up to 35 days), Study Treatment, and Follow-up. Screening involves exams, blood tests, heart tests, and imaging. Treatment includes oral medications with ramp-up dosing schedules and regular monitoring.

¿Cuál es la Condición que se está estudiando?

Chronic Lymphocytic Leukemia (CLL) in adults who have not received prior treatment

¿Quién puede participar en el Estudio?

People can join this study if they are 18 years or older and have a confirmed diagnosis of CLL. They must have organs that are working well and complete the required health checks before joining. If they can become pregnant, they must have a negative pregnancy test and agree to use birth control during the study.

Grupo etario
Adultos

¿Qué Implica?

This study is comparing two pairs of cancer medicines to see which one works better for treating CLL. One pair is sonrotoclax and zanubrutinib. The other pair is venetoclax and acalabrutinib. The study is open label, which means you and your doctor will know which medicines you are getting.

Detalles del Estudio

Título Completo
A Phase 3, Open-Label, Randomized Study of Sonrotoclax (BGB-11417) plus Zanubrutinib (BGB-3111) Compared with Venetoclax plus Acalabrutinib in Patients with Previously Untreated Chronic Lymphocytic Leukemia
Investigador Principal
Andrea Sitlinger, MD
Especialista en oncología hematológica
Número de Protocolo
IRB: PRO00119487
NCT: NCT07277231
Fase
Phase III
ClinicalTrials.gov
Estado de inscripción
Pronto disponible para inscripción
Apoye la investigación de Duke Health o rinda homenaje a un ser querido con un regalo conmemorativo.
Contribuya a Duke Health