Iberdomide Maintenance Vs Lenalidomide Maintenance Following ASCT (Multiple Myeloma) - Clinical Trial
¿Cuál es el Propósito de este estudio?
We are doing this study to find the most effective, safe dose of an experimental drug called iberdomide (the study drug). We want to know how well this study drug works in people with multiple myeloma when compared with a drug called lenalidomide after an autologous stem cell transplant.
Newly Diagnosed Multiple Myeloma (NDMM)
¿Quién puede participar en el Estudio?
Adults ages 18+ who:
- Are diagnosed with symptomatic MM
- Have received an autologous stem cell transplant
- Do not have progressive disease or clinical relapse following stem cell transplant
- Do not have smoldering myeloma, solitary plasmacytoma or nonsecretory myeloma
- Do not have known central nervous system/meningeal involvement of MM
Para obtener más información sobre quién puede participar en este estudio, comuníquese con el equipo del estudio al 919-668-1026.
¿Qué Implica?
Si decide unirse a este estudio, pasará por un período de detección para determinar si es elegible. Durante este período de detección, usted:
- Hacer un examen físico
- Hacerse un escáner del corazón (ECG)
- Realizar extracciones de sangre
- Provide urine samples
If you are eligible to join the study, you will get a random assignment (like a coin flip) to one of two different groups:
- One group will take a regimen of the study drug
- The other group will take a drug call lenalidomide
If you are assigned to the study drug group, you will take the study drug by mouth every day for the first 21 days of each 28-day drug cycle. The dose of the study drug that you get will depend on when you enter the study.
If you are assigned to get lenalidomide, you will take this drug every day. Your dose of lenalidomide will start at 10 mg once daily, and the study doctor might increase this dose to 15 mg after 3 cycles if they believe you will get a benefit from the change.
The total study drug regimen may take up to approximately 4 years, but this can vary depending on how you respond to the study drug.
Detalles del Estudio
