Celgene_CA057-001 CC92480 (Multiple Myeloma) - Clinical Trial

¿Cuál es el Propósito de este estudio?

We are doing this study to find out if an experimental drug called CC-92480 (the study drug) is a safe and effective treatment for multiple myeloma. We also want to figure out the most appropriate dose and schedule for giving the study drug to multiple myeloma patients.

¿Cuál es la Condición que se está estudiando?

Relapsed or Refractory Multiple Myeloma

¿Quién puede participar en el Estudio?

Adults ages 18+ who:

  • Have multiple myeloma that is not responding to therapy; OR
  • Have multiple myeloma that has come back after previous therapy

For more information about who can join this study, please contact the study team 919-668-0613.

Grupo etario
Adultos

¿Qué Implica?

This study has three periods: a screening period, the study drug period, and a follow-up period.

If you choose to join this study, during the screening period you will:

  • Hacer un examen físico
  • Realizar extracciones de sangre
  • Proporcionar muestras de orina
  • Have imaging tests (X-Ray, MRI/CT/PET scans)
  • Realizar una biopsia de médula ósea.

If you are eligible to join the study, you will take the study drug as directed by the study doctor. You will continue taking the study drug for as long as you and the study doctor believe that you are benefitting from it.

After you stop taking the study drug, we will keep in touch with you to see how you are doing.

Detalles del Estudio

Título Completo
Celgene: CA057-001 - A PHASE 3, TWO-STAGE, RANDOMIZED, MULTICENTER, OPEN-LABEL STUDY COMPARING CC-92480, BORTEZOMIB AND DEXAMETHASONE (480Vd) VERSUS POMALIDOMIDE, BORTEZOMIB AND DEXAMETHASONE (PVd) IN SUBJECTS WITH RELAPSED OR REFRACTORY MULTIPLE MYELOMA (RRMM)
Investigador Principal
Cristina Gasparetto, MD
Especialista en terapia celular
Número de Protocolo
IRB: PRO00112328
NCT: NCT05519085
Fase
Phase III
ClinicalTrials.gov
Estado de inscripción
Abierto para inscripción
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