EA1242 (RxFINE-Low) - Clinical Trial

¿Cuál es el Propósito de este estudio?

This study compares standard treatment that includes chemotherapy, hormone therapy, and ribociclib with a treatment that uses only hormone therapy and ribociclib. Researchers want to learn if chemotherapy is needed for all patients with this type of cancer.

¿Cuál es la Condición que se está estudiando?

People with breast cancer.

¿Quién puede participar en el Estudio?

Participants may be able to join if they are adults who are postmenopausal women or men with a certain type of hormone sensitive, HER2 negative breast cancer. They must have had breast cancer surgery within the past 16 weeks. People with certain forms of noninvasive breast cancer may also be eligible.

Grupo etario
Adultos

¿Qué Implica?

This study is comparing the usual treatment of chemotherapy followed by hormone therapy and ribociclib with treatment using hormone therapy and ribociclib alone in postmenopausal women and men. Researchers want to learn if patients can be treated successfully without chemotherapy.

Detalles del Estudio

Título Completo
EA1242: A Phase III Trial of Rx Therapy Guided by Genomic Risk Assessment For High Anatomic Stage ER-pos/HER2-neg Breast Cancer with RS<25 (RxFINE-Low)
Investigador Principal
Alexandra Thomas, MD, FACP
Especialista en oncología médica
Número de Protocolo
IRB: PRO00120668
NCT: NCT07391774
Fase
Phase III
ClinicalTrials.gov
Estado de inscripción
Abierto para inscripción
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Contribuya a Duke Health