SN2426 Recurrent Inoperable or Metastatic Cutaneous Squamous Cell Carcinoma - Clinical Trial

¿Cuál es el Propósito de este estudio?

Participants will first receive the study drug and be closely monitored for safety. In the second part, participants will be randomly assigned to receive either the study drug by injection or the standard treatment by IV. Treatment is given in 28 day cycles and may continue for up to 24 cycles.

¿Cuál es la Condición que se está estudiando?

This study is for people with a type of skin cancer that has spread or cannot be removed with surgery and who have a weakened immune system.

¿Quién puede participar en el Estudio?

Participants may be able to join if they are adults with this type of skin cancer. They cannot have received certain similar cancer treatments in the past year, had a lung transplant, or had a lung complication called graft versus host disease. People with cancer that spread to the brain may be eligible if it has not worsened after treatment.

Grupo etario
Adultos

¿Qué Implica?

This study is testing whether a study drug works better than a standard treatment at slowing or stopping advanced skin cancer in people with weakened immune systems. Researchers will also see if either treatment can help shrink the cancer.

Detalles del Estudio

Título Completo
Protocol SN2426, A Randomized Phase II Study of Amivantamab (JNJ-61186372) and hyaluronidase (rHuPH20) versus Cetuximab in Immunocompromised Participants with Recurrent Inoperable or Metastatic Cutaneous Squamous Cell Carcinoma
Investigador Principal
Número de Protocolo
IRB: PRO00120545
NCT: NCT07042295
Fase
Phase II
ClinicalTrials.gov
Estado de inscripción
Abierto para inscripción
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Contribuya a Duke Health