Exercise Prebreathe - Clinical Trial

¿Cuál es el Propósito de este estudio?

This study is about helping astronauts stay safe during moonwalks. When astronauts go to the moon, they wear special suits with lower air pressure, which can cause small bubbles to form in the body. These bubbles can cause a problem called decompression sickness, which may lead to pain or weakness.

To help prevent this, astronauts breathe pure oxygen before their moonwalk. In this study, people will breathe oxygen for about one hour while resting or doing different levels of exercise. After that, they will enter a special room that lowers air pressure to feel like being in a spacesuit. While inside, they will do light exercises and have ultrasound tests to look for bubbles in the body. This part lasts about six hours. The goal is to learn how well oxygen breathing and activity help prevent decompression sickness.

¿Cuál es la Condición que se está estudiando?

Healthy volunteers

¿Quién puede participar en el Estudio?

People can join this study if they are healthy men or women between 30 and 60 years old. They must be able to pass a test that checks how well they can exercise on a bike.

People cannot join if they are pregnant, smoke, or use illegal drugs. They also cannot join if they have lung problems, trouble clearing their ears during pressure changes, or take certain medicines for blood pressure, pain, sleep, or brain related conditions.

Grupo etario
Adultos

¿Qué Implica?

6 visits

Screening (includes physical exam, exercise test, altitude test, cardiac ultrasound - 5 hours)

VO2 measures - wear a mask that measures your work level during each exercise simulating the moon walk - 3 hours

Practice session - 4 hours

Study 1 - 9 hours

Study 2 - 9 hours

Study 3 - 9 hours

Detalles del Estudio

Título Completo
NASA Exercise Prebreathe Study
Investigador Principal
Richard E. Moon, MD, CM, FRCPC, FACP, FCCP
Especialista en anestesiología
Número de Protocolo
IRB: PRO00120426
NCT: NCT07702539
Fase
Fase N/A
ClinicalTrials.gov
Estado de inscripción
Abierto para inscripción
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