Astellas- Drug ASP546C for CLDN18.2-expressing solid tumors (546C-CL-0201) - Clinical Trial

¿Cuál es el Propósito de este estudio?

If you join this study, you will receive a medicine called ASP546C through a vein every three weeks. You will also give blood and urine samples so doctors can check your health and how your body responds to the treatment. During the study, you will have regular scans such as CT or MRI to see how your cancer is changing.

¿Cuál es la Condición que se está estudiando?

CLDN18.2-Expressing Cancers

¿Quién puede participar en el Estudio?

People can join this study if they are adults who have cancer that has spread or grown and cannot be cured with surgery. The cancer must have a special marker called CLDN 18.2. They must have already tried at least one treatment before. The study includes several types of cancer, such as cancers of the stomach and food tube, pancreas, bile ducts, colon, lungs, ovaries, and breast.

Grupo etario
Adultos

¿Qué Implica?

The purpose of this study is to see if a new medicine called ASP546C is safe and works well for certain cancers. These cancers have a special marker called CLDN18.2. Researchers want to learn if the medicine can help treat these cancers and improve patient health.

Detalles del Estudio

Título Completo
[546C-CL-0201] A Phase 1b/2 Open-label Study to Assess the Safety and Efficacy of ASP546C in Participants with CLDN18.2-expressing Locally Advanced Unresectable or Metastatic Gastroesophageal Adenocarcinoma, Pancreatic Adenocarcinoma or Other Solid Tumor Types
Investigador Principal
John H. Strickler, MD
Especialista en oncología médica
Número de Protocolo
IRB: PRO00119707
NCT: NCT07488676
Fase
Phase I/II
ClinicalTrials.gov
Estado de inscripción
Abierto para inscripción
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Contribuya a Duke Health