Alterome- ALTA3263 for Advanced Solid Tumors With KRAS Mutations - Clinical Trial

¿Cuál es el Propósito de este estudio?

In this study, you will take a medicine called ALTA3263 by mouth every day. You will keep taking it until your cancer gets worse or until you need to stop because of strong or frequent side effects. While you are in the study, you will go to the clinic for regular visits. During these visits, the study team will do tests to check your health and collect information for research.

¿Cuál es la Condición que se está estudiando?

Advanced Solid Tumors With KRAS

Mutations

¿Quién puede participar en el Estudio?

People can join this study if they are at least 18 years old and have a solid tumor cancer that has a specific change in a gene called KRAS. This change can be found in the tumor or in the blood. They must also have cancer that cannot be removed with surgery or has spread to other parts of the body.

Grupo etario
Adultos

¿Qué Implica?

This study is being done to learn if a new medicine called ALTA3263 is safe to use. The study will also look at both the helpful and harmful effects of the medicine when it is given in different amounts. Researchers want to understand how the drug affects the body so they can learn the best and safest dose to use in future studies.

Detalles del Estudio

Título Completo
3263-001: A Phase 1/1b Multiple Cohort Trial of ALTA3263 in Patients With Advanced Solid Tumors With KRAS Mutations
Investigador Principal
John H. Strickler, MD
Especialista en oncología médica
Número de Protocolo
IRB: PRO00119651
NCT: NCT06835569
Fase
Fase I
ClinicalTrials.gov
Estado de inscripción
Abierto para inscripción
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Contribuya a Duke Health