DSP107 in combination with atezolizumab in comparison with fruquintinib in CRC - Clinical Trial

¿Cuál es el Propósito de este estudio?

People in this study will be placed into one of two groups by chance, like flipping a coin. One group will get two medicines called DSP107 and Atezolizumab together. The other group will get a medicine called Fruquintinib by itself. Each treatment cycle lasts 4 weeks and can continue for up to 2 years. Doctors will check health and safety during the study. After the last dose, there will be a follow-up period of up to 90 days.

¿Cuál es la Condición que se está estudiando?

Advanced Microsatellite Stable Colorectal Cancer

¿Quién puede participar en el Estudio?

People can join this study if they are 18 years or older and are expected to live for more than 3 months. They must have a type of colon cancer called microsatellite stable (MSS) or proficient mismatch repair (pMMR) colorectal cancer.

Grupo etario
Adultos

¿Qué Implica?

The goal of this study is to learn if people with a type of colon cancer called microsatellite stable colorectal cancer do better when treated with two medicines, DSP107 and Atezolizumab, compared to those who get Fruquintinib.

Detalles del Estudio

Título Completo
A Randomized, Open-label, Phase 2b Study to Compare the Efficacy of DSP107 in Combination with Atezolizumab Versus Fruquintinib in Patients with Advanced Microsatellite Stable Colorectal Cancer
Investigador Principal
Nicholas C. DeVito, MD
Especialista en oncología médica
Número de Protocolo
IRB: PRO00119461
NCT: NCT07235293
Fase
Phase II
ClinicalTrials.gov
Estado de inscripción
Abierto para inscripción
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Contribuya a Duke Health