DCA09: VS-041-102 - Clinical Trial

¿Cuál es el Propósito de este estudio?

This is a randomized trial, with some participants receiving the study drug and some receiving placebo. The study drug (an oral pill) will be taken daily for 28 days. The total duration of study activities is 9 weeks.

¿Cuál es la Condición que se está estudiando?

This study is enrolling patients with Heart Failure with Preserved Ejection Fraction (HFpEF).

¿Quién puede participar en el Estudio?

People can join this study if they are over 50 years old and have a type of heart failure called HFpEF, which means the heart pumps well but does not relax and fill properly. They cannot have other serious heart conditions, such as valve problems, diseases of the heart lining, or weakened heart muscle. They also cannot have had recent heart attacks, blocked heart arteries, abnormal heart rhythms, or major heart surgery. People with certain implanted heart devices are also not able to join this study.

Grupo etario
Adultos

¿Qué Implica?

This trial is testing the safety and tolerability of a novel drug that targets the fibrosis (hardening or scarring) that occurs in patients with heart failure.

Detalles del Estudio

Título Completo
DCA09: A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants with Heart Failure with Preserved Ejection Fraction (HFpEF)
Investigador Principal
Marat Fudim, MD, MHS
Especialista en insuficiencia cardíaca avanzada
Número de Protocolo
IRB: PRO00119403
NCT: NCT07219511
Fase
Fase I
ClinicalTrials.gov
Estado de inscripción
Abierto para inscripción
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Contribuya a Duke Health