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ABBV-400 Monotherapy to the Current SOC in ctDNA positive CRC and NED (M24-534) - Clinical Trial

¿Cuál es el Propósito de este estudio?

People in this study will be in one of two groups. One group will get a medicine called ABBV-400 through an IV every 21 days. The other group will not get medicine but will have blood tests for cancer DNA and imaging scans to check for cancer.

¿Cuál es la Condición que se está estudiando?

This study is for people who had colon or rectal cancer (called CRC) and already finished extra treatment after surgery, called adjuvant therapy. These people have a blood test that shows cancer DNA (called ctDNA), but their scans do not show any cancer.

¿Quién puede participar en el Estudio?

The person must be at least 18 years old. They have a type of cancer called oligometastatic, which is in stage II, III, or IVa. Right now, there are no signs of cancer showing up on their scans.

Grupo etario
Adultos

¿Qué Implica?

The purpose of this study is to find out if a medicine called telisotuzumab adizutecan, also called ABBV-400, can help stop cancer from coming back and maybe even cure people with colorectal cancer. This study is for people who had surgery and chemotherapy and still have cancer DNA in their blood after treatment.

Detalles del Estudio

Título Completo
Colorectal Cancer: A Phase 2, Randomized, Open-Label Study Comparing Telisotuzumab Adizutecan (ABBV-400) Monotherapy to the Current Standard of Care in Subjects with Post Adjuvant ctDNA Positive Colorectal Cancer and No Radiographic Evidence of Disease (NED)
Investigador Principal
Aman Opneja, MBBS
Especialista en oncología médica
Número de Protocolo
IRB: PRO00119303
NCT: NCT07023289
Fase
Phase II
ClinicalTrials.gov
Estado de inscripción
Pronto disponible para inscripción
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Contribuya a Duke Health