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PH-L19IL2TNFSCC - Clinical Trial

¿Cuál es el Propósito de este estudio?

L19IL2/L19TNF

¿Cuál es la Condición que se está estudiando?

Advanced Cutaneous Squamous Cell Carcinoma

¿Quién puede participar en el Estudio?

People can join this study if they have a confirmed case of locally advanced cutaneous squamous cell carcinoma. They must have at least one tumor on or under the skin that can be measured and injected with the study medicine. They must also have cancer that has gotten worse after taking, or cannot tolerate, a type of treatment called immune checkpoint inhibitors. A team of doctors must agree on this. People can also join if their cancer has spread to nearby areas, such as lymph nodes or skin in between the main tumor area.

Grupo etario
Adultos

¿Qué Implica?

This study wants to find out how well the combination treatment L19IL2/L19TNF works for people with Cutaneous Squamous Cell Carcinoma. Researchers also want to learn how well patients handle the medicine and whether this treatment helps them live longer.

Detalles del Estudio

Título Completo
A Phase 2 study of intratumoral administration of L19IL2/L19TNF in locally advanced Cutaneous Squamous Cell Carcinoma patients progressing on or intolerant to systemic treatment
Investigador Principal
Melodi J. Whitley, MD, PhD
Especialista en dermatología
Número de Protocolo
IRB: PRO00119223
NCT: NCT07228442
Fase
Phase II
ClinicalTrials.gov
Estado de inscripción
Pronto disponible para inscripción
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Contribuya a Duke Health