GSK223559 Ph I/II study of GSK5733584 in combo with anti-cancer therapies for adv solid tumors - Clinical Trial

¿Cuál es el Propósito de este estudio?

This study tests a new cancer medicine. It has 3 parts:

- Screening (up to 28 days): You'll get tests like heart checks, scans, and blood work.

- Treatment: You'll visit the clinic every 3 weeks to get the study drug. There are different groups testing the drug with other treatments for cancers like ovarian and endometrial.

- Follow-Up: After treatment, you'll have check-ups at 30, 60, and 90 days, plus long-term follow-up with more tests.

¿Cuál es la Condición que se está estudiando?

Adults with advanced solid tumors

¿Quién puede participar en el Estudio?

Who can join this study:

- Adults with solid tumors, which are a type of cancer.

- People with advanced or returning endometrial cancer who didn’t get better with regular treatments or can’t use them.

- People whose cancer got worse after at least one kind of treatment.

- People with advanced ovarian, fallopian tube, or peritoneal cancer confirmed by lab tests.

Grupo etario
Adultos

¿Qué Implica?

Doctors are doing a study to test a new cancer medicine called GSK5733584. They want to see if it's safe to use by itself or with other cancer medicines. The goal is to find out if it can help treat solid tumors (a kind of cancer) more effectively.

Detalles del Estudio

Título Completo
A Phase I/II Randomized Multi-Cohort Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 in Combination with Anti-Cancer Agents in Participants with Advanced Solid Tumors
Investigador Principal
Angeles Alvarez Secord, MD, MHSc
Especialista en oncología ginecológica
Número de Protocolo
IRB: PRO00118137
NCT: NCT06796907
Fase
Phase I/II
ClinicalTrials.gov
Estado de inscripción
Abierto para inscripción
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Contribuya a Duke Health