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Amgen DeLLphi309 Recurrent Small Cell Lung Cancer - Clinical Trial

What is the Purpose of this Study?

We are doing this study to find out if an experimental drug called tarlatamab (the study drug) is a safe and effective option for people who have small cell lung cancer (SCLC) that has progressed and spread to other parts of the body.

What is the Condition Being Studied?

Small Cell Lung Carcinoma (SCLC)

Who Can Participate in the Study?

Adults ages 18+ who:

  • Are diagnosed with SCLC
  • Have received at least one previous line of treatment with a platinum-based regimen
  • Had their disease get worse after treatment

For more information about who can join this study, please contact the study team at annemarie.peters@duke.edu.

Grupo etario
Adultos

What is Involved?

If you choose to join this study, you will get a random assignment (by chance) to 1 of 3 groups. Depending on your assignment, you might:

  • Get a dose of the study drug every 2 weeks; OR
  • Get a dose of the study drug every 3 weeks; OR
  • Get a dose of the study drug every 4 weeks

The study drug is given as an intravenous (IV) infusion through a vein. The length of time you receive the study drug will depend on how you respond to it.

Study Details

Full Title
A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects with Small Cell Lung Cancer (SCLC)(DeLLphi-309)
Principal Investigator
Especialista en oncología médica
Protocol Number
IRB: PRO00117430
NCT: NCT06745323
Phase
Phase II
ClinicalTrials.gov
Estado de inscripción
Pronto disponible para inscripción