Pan-KRAS Inhibitor LY4066434 +/- SOC drugs in KRAS Mutant Solid Tumors (J5Q-OX-JRDA) - Clinical Trial
¿Cuál es el Propósito de este estudio?
We are doing this study to find out if an experimental drug called LY4066434 (the study drug) is a safe and effective option for patients who have solid tumor(s) with a KRAS mutation. We want to know how well the study drug works on its own and in combination with other anti-cancer therapies.
Tumores que tienen una mutación en KRAS G12C, G12D, G12V, G12A, G12S o G13D
¿Quién puede participar en el Estudio?
Adults ages 18+ who:
- Have evidence of KRAS G12C, G12D, G12V, G12A, G12S, or G13D mutation in their tumor(s)
- Are not pregnant or breastfeeding
For more information, contact the study team at dana.a.warren@duke.edu.
¿Qué Implica?
If choose to join this study, you will get a random assignment (like a coin flip) to either take the study drug on its own or in combination with other, approved cancer therapies.
If you are assigned to take the study drug alone, you will take it by mouth twice each day. If you are assigned to get the study drug in combination with other drugs (cetuximab and/or chemotherapy), you will get another random assignment to take 1 of 6 possible drug combinations.
Detalles del Estudio
