Corbus CRB-601-01 (Solid Tumors) - Clinical Trial

¿Cuál es el Propósito de este estudio?

We are doing this study to find out if an experimental drug called CRB-601 (the study drug) is a safe and effective option for people who have cancers with advanced solid tumors that did not improve with standard treatment.

¿Cuál es la Condición que se está estudiando?

Advanced Solid Tumor Cancers

¿Quién puede participar en el Estudio?

Adultos de 18 a 64 años que:

  • Are diagnosed with an advanced or metastatic solid tumor
  • Had their disease progress after at least 1 line of previous treatment

For more information about who can join this study, please contact the Center for Cancer Immunotherapy at CCI-TrialReferrals@duke.edu.

Grupo etario
Adultos

¿Qué Implica?

If you choose to join this study, you will get an assignment to 1 of 3 different dose levels of the study drug. These dose levels might be:

  • 3 milligrams for each kilogram of body weight (3 mg/kg); OR
  • 10 mg/kg; OR
  • 30 mg/kg

The dose level you receive will depend on when you join the study. The study team can let you know what dose level is open when you make your decision.

The study drug is given as an intravenous (IV) infusion every 2 weeks.

Detalles del Estudio

Título Completo
A Phase 1/2 Study to Investigate the Safety, Pharmacokinetics and Efficacy of CRB-601, a Monoclonal Antibody against Integrin αvβ8, in Patients with Advanced Solid Tumors
Investigador Principal
Especialista en oncología médica
Número de Protocolo
IRB: PRO00116951
NCT: NCT06603844
Fase
Phase I/II
ClinicalTrials.gov
Estado de inscripción
Abierto para inscripción