LY3962673 for KRAS G12D-mutated solid tumors - Clinical Trial

¿Cuál es el Propósito de este estudio?

We are doing this study to find out if an experimental drug called LY3962673 (the study drug) is a safe and effective option for cancer that has a KRAS G12D mutation. We are also trying to find the best dose level to use.

¿Cuál es la Condición que se está estudiando?

Solid Tumors with KRAS G12D Mutation

¿Quién puede participar en el Estudio?

Adults ages 18+ who:

  • Are diagnosed with a solid tumor form of cancer
  • Have disease that is inoperable, advanced, or metastatic
  • The tumor tests positive for a KRAS G12D mutation

For more information, contact the study team at dana.a.warren@duke.edu.

Grupo etario
Adultos

¿Qué Implica?

Si elige unirse a este estudio, podrá:

  • Take the study drug by mouth once or twice every day
  • Depending on which arm of the study you are in, you may also get standard anti-cancer drugs every 1 to 2 weeks
  • Hágase biopsia del tumor
  • Give blood and urine samples
  • Realice tomografías computarizadas o resonancias magnéticas de manera regular.

Detalles del Estudio

Título Completo
[J5J-OX-JZZA] Moonray-01, A Phase 1a/1b Trial of LY3962673 in Participants with KRAS G12D-Mutant Solid Tumors
Investigador Principal
John H. Strickler, MD
Especialista en oncología médica
Número de Protocolo
IRB: PRO00116471
NCT: NCT06586515
Fase
Fase I
ClinicalTrials.gov
Estado de inscripción
Abierto para inscripción
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