DEPTH Trial (Emphysema in People Living with HIV) - Clinical Trial

What is the Purpose of this Study?

If you choose to join this study, you will complete up to 10 study visits and 2 phone call check-ins over 72 weeks. This study includes:

  • Pulmonary function tests (how well your lungs are working)
  • CT scans of the chest (a special type of imaging that creates 3D X-ray images)
  • Extracción de sangre
  • Cuestionarios

During the study, you will be randomized (like flipping a coin) to get either:

  • The study drug (Doxycycline) by mouth twice a day for 72 weeks; OR
  • A placebo (sugar pill) by mouth twice a day for 72 weeks
  • What is the Condition Being Studied?

    Enfisema en personas que viven con VIH

    Who Can Participate in the Study?

    Adults ages 30+ who:

    • Are living with HIV
    • Have smoking-related lung disease

    For more information about who can join this study, please contact the study team at depth-trial@duke.edu or 919-684-2285.

    Grupo etario
    Adultos

    What is Involved?

    Estamos realizando este estudio para aprender más sobre si la doxiciclina (un medicamento antibiótico) ayudará a ralentizar la progresión del enfisema o EPOC.

    Study Details

    Full Title
    Doxiciclina para enfisema en personas que viven con VIH (ensayo DEPTH)
    Principal Investigator
    Especialista en neumología
    Protocol Number
    IRB: PRO00111021
    NCT: NCT05382208
    Phase
    Phase II
    ClinicalTrials.gov
    Estado de inscripción
    Abierto para inscripción