Macrophage Regulation of Ozone-Induced Lung Inflammation (MOLI Study for Healthy Volunteers) - Clinical Trial
¿Cuál es el Propósito de este estudio?
We are doing this study to understand how environmental exposures may be involved in lung function. We want to find out how immune cells in the lungs are affected by irritants that are present in the environment.
¿Cuál es la Condición que se está estudiando?
Lung Function of Health Adults
¿Quién puede participar en el Estudio?
Adultos de 18 a 55 años que:
- Are in good general health; OR
- Have a history of COVID-19 that resulted in mild symptoms and no evidence of a lower respiratory tract infection and no need for supplemental oxygen; OR
- Have a history of COVID-19 that resulted in a documented lower respiratory tract infection at least 6 months ago and have since recovered and are breathing normally
For more information, contact the study team at claudia.salazar@duke.edu.
Grupo etario
Adultos
¿Qué Implica?
Si elige unirse a este estudio, podrá:
- Have a 1-day screening visit that includes a blood draw and breathing tests
- Have a 2-day series of testing that includes a blood draw and a brief breathing test before and after inhaling air that contains either filtered air or ozone
- Have a bronchoscopy
- Have a second 2-day series of testing 18-20 days after the first series (whatever type of air you did not get the first time will be delivered to you this time)
Each study visit to our clinic will take about 3-3.5 hours. The study will take about 4-6 weeks to finish.
Detalles del Estudio
Título Completo
Macrophage Regulation of Ozone-Induced Lung Inflammation (MOLI Study)
Investigador Principal
Número de Protocolo
IRB:
PRO00110603
NCT:
NCT05773001
Fase
Fase N/A
ClinicalTrials.gov
Ver en ClinicalTrials.gov
Estado de inscripción
Abierto para inscripción