A081801 (Lung Cancer) - Clinical Trial

What is the Purpose of this Study?

We are doing this study to see if combining immunotherapy with chemotherapy is a better treatment than chemotherapy alone for NSCLC.

What is the Condition Being Studied?

Cáncer de pulmón de células no pequeñas (CPCNP)

Who Can Participate in the Study?

Adults 18 and older who:

  • Have lung cancer that has been removed while on Duke Cancer Study A151216
  • Had their surgery between 33-77 days ago
  • Are negative for the genetic markers EGRF and ALK
Grupo etario
Adultos

What is Involved?

If you choose to join this study, you will get a random assignment (fair, equal chance) to 1 of 3 groups:

  • One group will receive only chemotherapy for 3 months
  • Another group will receive chemotherapy for 3 months followed by immunotherapy for up to 1 year
  • A third group will receive chemotherapy and immunotherapy together for 3 months followed by immunotherapy for up to 10 months
  • Regardless of group assignment, all study participants will:

    • Get check-ups from your doctor every 3 months for the first 2 years after treatment
    • Get check-ups from your doctor every 6 months for the 3rd, 4th, and 5th years after treatment
    • Get a yearly check-up from your doctor for 5 more years once you hit the 5-year mark after treatment

    Altogether, you will continue to see your doctor and study team for 10 years after treatment.

    Study Details

    Full Title
    Alliance A081801: Integration of Immunotherapy into Adjuvant Therapy for Resected NSCLC: ALCHEMIST CHEMO-IO
    Principal Investigator
    Protocol Number
    IRB: PRO00106593
    NCT: NCT04267848
    Phase
    Phase III
    ClinicalTrials.gov
    Estado de inscripción
    Abierto para inscripción
    Participate