Genetic Study for SCD and CHD (Heart Disease) - Clinical Trial
What is the Purpose of this Study?
We are doing this study to learn more about the cause of cardiac (heart) disease or sudden unexplained death, which is something that can run in families.
Some conditions that we are looking at are:
- Cardiomyopathies (a disease of the heart muscle that makes it harder for your heart to pump blood to the rest of your body) like hypertrophic cardiomyopathy, dilated cardiomyopathy, or arrhythmogenic cardiomyopathy (also called right ventricular cardiomyopathy)
- Arrhythmia syndromes (a problem with the rate or rhythm of the heartbeat, either too slow or too fast) like long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, or short QT syndrome
- Sudden cardiac arrest or unexplained sudden death (heart stops suddenly) in someone less than 50 years of age, including sudden infant death syndrome (SIDS)
- Individuals with genetic mutations (variants) in genes that can lead to cardiac disease which include (LMNA, ATP1A3, and TAX1BP3)
What is the Condition Being Studied?
Children and adults with unexplained sudden death or heart disease that was diagnosed before the age of 80 years old
Who Can Participate in the Study?
Children and adults can participate in this study.
For more information about who can be in this study, please contact the study team at landstromlab@duke.edu.
Grupo etario
Adults, Children
What is Involved?
Si elige unirse a este estudio, podrá:
- Give a blood sample (must be able to travel to Duke for this)
- We may also ask family members to join the study to learn more about a disease running in the family
Study Details
Full Title
The Genetic and Molecular Basis of Sudden Cardiac Death-Predisposing Diseases and Congenital Heart Conditions
Principal Investigator
Especialista en electrofisiología
Protocol Number
IRB:
PRO00094341
Phase
Phase
N/A
Estado de inscripción
Abierto para inscripción